NMDARS DRIVE THE EXPRESSION OF NEUROPSYCHIATRIC DISORDER RISK GENES WITHIN GABAERGIC INTERNEURON SUBTYPES IN THE JUVENILE BRAIN

NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain

Medial ganglionic eminence (MGE)-derived parvalbumin (PV)+, somatostatin (SST)+and Neurogliaform (NGFC)-type Left Post Cover cortical and hippocampal interneurons, have distinct molecular, anatomical, and physiological properties.However, the molecular mechanisms regulating their maturation remain poorly understood.Here, via single-cell transcripto

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Performance comparison of physics-based and machine learning assisted multi-fidelity methods for the management of coastal aquifer systems

In this work we investigate the performance of various lower-fidelity models of seawater intrusion in coastal aquifer management problems.The variable density model is considered as the high-fidelity model and a pumping optimization framework is applied on a hypothetical coastal aquifer system in order to calculate the optimal pumping rates Booster

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The Remuneration Policy in the Budgetary Sphere of Ukraine: Main Trends, Shortcomings, Suggestions for Improvement

The aim of the work is to identify the main trends and shortcomings of the remuneration policy in the budgetary sphere of Ukraine and develop proposals for its improvement.There determined the main problems of the remuneration policy in the budgetary sphere, including the low level and unsatisfactory wage differentiation, intersectoral imbalances i

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